GABA CONFUSION

Keep this in mind when your patients make the switch.

Click here for previous newsletters.

1. Counselling Conundrum: a real question from a patient

2. Concise Conclusion: a straight-forward patient-friendly answer 

3. Quick Wrap-up 

Clearly, there are nuances that may not be captured in this format. The goal here is to provide you with helpful counselling tips which often draw from multiple sources or those which are not commonly accessed by busy healthcare providers serving the community.

Counselling Conundrum: "My doctor switched me from gabapentin to pregabalin. Isn't it the same?"

Concise Conclusion: Excellent question! While they work the same, pregabalin is more readily absorbed, and so lower doses are required to get a similar benefit. More 'bang for your buck'. You probably were taking a large amount of gabapentin and starting to see less benefit.

Quick Wrap-up: Absorption of gabapentin is saturable, which means at some point higher doses don't yield higher concentrations - it is not a linear response.

Dive Deeper

1) https://www.pharmacytimes.com/view/how-gabapentin-differs-from-pregabalin

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